In traditional GC-MS/MS analysis, the technique that is most often utilized is electron ionization (EI). However in some cases, compounds can be labile and fragment heavily when using EI, which can make it difficult to identify them via NIST library searches or to generate selective MRMs. Chemical ionization (CI) operated in both positive and negative ion modes can help reduce the fragmentation significantly. In CI ions are produced via collisions with the reagent gas (e.g. methane, ammonia, or isobutane). By utilizing the dedicated CI ionization source available on the Xevo TQ-GC, which was designed for extended robustness and rapid tool-free changeover, both EI and CI experiments can be performed on the same system.
This technoloy brief demonstrates how switching between EI and CI on the Xevo TQ-GC is very simple, with no tools required, and the changeover takes less than 10 min.
To download your copy of this technology brief complete the form opposite.
Registrants for this technology brief are covered by the Eclipse Business Media Privacy Policy.
Eclipse Business Media Ltd, Regd in England, No. 06513189, Woodview, Bull Lane Industrial Estate, Sudbury, CO10 0FD, United Kingdom, T +44 (0)161 818 7434, info@sepscience.com
Eclipse Business Media Ltd needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy or contact privacy@labxmediagroup.com
Copyright © 2023. All rights reserved