This application note describes an MRM-based method for detection and quantitation of phenol and nine substituted phenols in reservoir water, without pre-treatment and pre-concentration. Coupled with a pentafluorophenyl column, treated water and reservoir water were analysed on a triple quadrupole LC/MS/MS with an APCI interface.
This method demonstrated high sensitivity detection of all ten phenols in water samples that were injected directly into the LC/MS/MS. Furthermore, with fast gradient elution of 8 minutes, the limit of detection achieved by this method was better than 0.1 µg/L for most of the phenol compounds.
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